Article
Improved survival in women with BRCA-associated ovarian carcinoma.
Cancer - 1 May 2003
Cass Ilana, Baldwin Rae Lynn, Varkey Taz, Moslehi Roxana, Narod Steven A, Karlan Beth Y
Abstract excerpt
BACKGROUND: The objective of this study was to determine the clinical characteristics, treatment response, and frequency of p53 overexpression in Ashkenazi Jewish women with hereditary ovarian carcinoma. METHODS: Seventy-one Jewish women with epithelial ovarian carcinoma (EOC) were tested for the three BRCA founder mutations using single-strand conformation polymorphism analysis, heteroduplex analysis, and...
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