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Article

Selecting Patients with Ovarian Cancer for Germline BRCA Mutation Testing: Findings from Guidelines and a Systematic Literature Review.

Advances in therapy - 1 Feb 2016

Eccles Diana M, Balmaña Judith, Clune Joe, Ehlken Birgit, Gohlke Annegret, Hirst Ceri, Potter Danielle, Schroeder Claudia, Tyczynski Jerzy E, Gomez Garcia Encarnacion B

Abstract excerpt

INTRODUCTION: One of the most significant risk factors for the development of ovarian cancer (OC) is a genetic mutation in BRCA1 (breast cancer gene 1) or BRCA2. Here we describe the impact of previous and current guidance on BRCA testing practices and provide evidence about which characteristics best identify patients with OC and an underlying germline BRCA mutation. METHODS: A search was conducted for...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26809252
DOI: 10.1007/s12325-016-0281-1

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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