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Article

Alternatives to risk-reducing surgery for ovarian cancer.

Annals of oncology : official journal of the European Society for Medical Oncology - 1 Nov 2013

Gadducci A, Sergiampietri C, Tana R

Abstract excerpt

BRCA1 and BRCA2 mutation carriers have an 18%-60% and 11%-27% lifetime risk of developing ovarian carcinoma, respectively. Prophylactic bilateral salpingo-oophorectomy reduces the risk of this malignancy by up to 96%. Gynecological screening programs with periodical trans-vaginal ultrasound and serum CA125 assay have been widely used in women at hereditary high risk of ovarian carcinoma, but clinical results have...

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Identifiers

PMID: 24131970
DOI: 10.1093/annonc/mdt311

Genes

BRCA1
BRCA2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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