Article
Rapid and simultaneous detection of vitamin D receptor gene polymorphisms by a single ARMS-PCR assay.
Molecular diagnosis & therapy - 1 Feb 2014
Jafari Mohammad, Pirouzi Aliyar, Anoosheh Saber, Farnia Parisa, Tajik Nader
Abstract excerpt
BACKGROUND: Vitamin D has various roles in many biological actions such as calcium homeostasis, cell proliferation, and cell differentiation to many target tissues. These effects are mediated by the active form of vitamin D, 1,25(OH)2D3, which binds to a cytoplasmic protein called vitamin D receptor (VDR). VDR gene has four common single nucleotide polymorphisms (SNPs) that are defined by the presence of...
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