Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polynucleotide phosphorylase (PNPase) is required for Salmonella enterica serovar Typhimurium colonization in swine.

Microbial pathogenesis - 1 Dec 2013

Bearson S M D, Bearson B L, Lee I S, Kich J D

Abstract excerpt

The pnp gene encodes polynucleotide phosphorylase, an exoribonuclease involved in RNA processing and degradation. A mutation in the pnp gene was previously identified by our group in a signature-tagged mutagenesis screen designed to search for Salmonella enterica serovar Typhimurium genes required for survival in an ex vivo swine stomach content assay. In the current study, attenuation and colonization potential...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Feces
Share to Gastrointestinal Tract
Share to Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Polyribonucleotide Nucleotidyltransferase

Share to Salmonella Infections, Animal

Share to Salmonella typhimurium

Share to Swine Diseases

Source

Identifiers

PMID: 24126127
DOI: 10.1016/j.micpath.2013.10.001

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polynucleotide phosphorylase (PNPase) is required for Salmonella enterica serovar Typhimurium colonization in swine.PMID 24126127Read ↗

A mutation in the poxA gene of Salmonella enterica serovar Typhimurium alters protein production, elevates susceptibility to environmental challenges, and decreases swine colonization.Semantic proximity Read ↗

Polynucleotide phosphorylase negatively controls spv virulence gene expression in Salmonella enterica.Semantic proximity Read ↗

Role in virulence and protective efficacy in pigs of Salmonella enterica serovar Typhimurium secreted components identified by signature-tagged mutagenesisSemantic proximity Read ↗

Identification of single-nucleotide variants associated with susceptibility to Salmonella in pigs using a genome-wide association approach.Semantic proximity Read ↗

Systemic and enteric colonization of pigs by a hilA signature-tagged mutant of Salmonella choleraesuis.Semantic proximity Read ↗

Genome-scale TraDIS reveals dynamic and conserved fitness requirements of <i>Salmonella</i> Typhimurium across sequential host niches during porcine infectionSemantic proximity Read ↗

Novel attenuated Salmonella enterica serovar Choleraesuis strains as live vaccine candidates generated by signature-tagged mutagenesis.Semantic proximity Read ↗

Characterization of colonization-deficient mutants of Actinobacillus suis.Semantic proximity Read ↗

In vivo effect of a TLR5 SNP (C1205T) on Salmonella enterica serovar Typhimurium infection in weaned, specific pathogen-free Landrace piglets.Semantic proximity Read ↗

Polynucleotide phosphorylase independently controls virulence factor expression levels and export in Yersinia spp.Semantic proximity Read ↗

Identification of genes affecting Salmonella enterica serovar enteritidis infection of chicken macrophages.Semantic proximity Read ↗

Long-Term Survival of Campylobacter jejuni at Low Temperatures Is Dependent on Polynucleotide Phosphorylase ActivitySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.