Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Endothelin-1 gene polymorphisms and risk of chemoresistant pediatric osteosarcoma.

Pediatric blood & cancer - 1 Apr 2014

Zhou Yu, Liu Bo, Wang Min, Ni Jiangdong

Abstract excerpt

BACKGROUND: Osteosarcoma (OS) is the most common childhood bone cancer. Chemoresistance is the principal reason for poor survival and disease recurrence in OS patients, and ET-1 reportedly plays an important role in the development of chemoresistance in OS cells. In the present study, we for the first time explored the association of endothelin-1 (ET-1) SNPs and haplotypes with the risk of chemoresistant...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antineoplastic Combined Chemotherapy Protocols
Share to Bone Neoplasms
Share to Drug Resistance, Neoplasm

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Endothelin-1

Share to Follow-Up Studies

Share to Neoplasm Staging

Share to Osteosarcoma

Share to Prognosis

Source

Identifiers

PMID: 24123836
DOI: 10.1002/pbc.24790

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Endothelin-1 gene polymorphisms and risk of chemoresistant pediatric osteosarcoma.PMID 24123836Read ↗

Focus on Hypoxia-Related Pathways in Pediatric Osteosarcomas and Their DruggabilitySemantic proximity Read ↗

Endothelin-1 single nucleotide polymorphisms and risk of pulmonary metastatic osteosarcoma.Semantic proximity Read ↗

Identification of genetic variants in pharmacokinetic genes associated with Ewing Sarcoma treatment outcome.Semantic proximity Read ↗

ATIC Gene Polymorphism and Histologic Response to Chemotherapy in Pediatric Osteosarcoma.Semantic proximity Read ↗

TCERG1L allelic variation is associated with cisplatin-induced hearing loss in childhood cancer, a PanCareLIFE studySemantic proximity Read ↗

Methotrexate in pediatric osteosarcoma: response and toxicity in relation to genetic polymorphisms and dihydrofolate reductase and reduced folate carrier 1 expression.Semantic proximity Read ↗

Novel insights and therapeutic interventions for pediatric osteosarcoma.Semantic proximity Read ↗

Pediatric Malignant Bone Tumors: A Review and Update on Current Challenges, and Emerging Drug Targets.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.