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Article

Endothelin-1 single nucleotide polymorphisms and risk of pulmonary metastatic osteosarcoma.

PloS one - 1 Jan 2013

Zang Xiaofang, Zhou Yong, Huang Zufa, Zhang Chaoyue

Abstract excerpt

Pulmonary metastases are the major cause of death of osteosarcoma (OS) patients. Endothelin-1 (ET-1) reportedly plays an important role in OS metastasis. In the present study, we for the first time explored the association of ET-1 SNPs with the risk of pulmonary metastatic OS. We genotyped three SNPs (rs1800541, rs2070699 and rs5370) in the ET-1 gene in a case-control study, using 260 pairs of age-, sex-,...

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Identifiers

PMID: 24069190
DOI: 10.1371/journal.pone.0073349
PMCID: PMC3771903

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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