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Article

Corticotropin releasing hormone receptor 2 (CRHR-2) gene is associated with decreased risk and severity of posttraumatic stress disorder in women.

Depression and anxiety - 1 Dec 2013

Wolf Erika J, Mitchell Karen S, Logue Mark W, Baldwin Clinton T, Reardon Annemarie F, Humphries Donald E, Miller Mark W

Abstract excerpt

BACKGROUND: The corticotropin releasing hormone (CRH) system has been implicated in a variety of anxiety and mood-based symptoms and disorders. CRH receptor-2 (CRHR-2) plays a role in attenuating biological responses to stressful life events and trauma, making the CRHR-2 gene a strong candidate to study in relationship to PTSD. METHODS: The sample was 491 trauma-exposed white non-Hispanic veterans and their...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24123648
DOI: 10.1002/da.22176
PMCID: PMC3855198

Genes

CRH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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