Article
Fall risk and gait in Parkinson's disease: the role of the LRRK2 G2019S mutation.
Movement disorders : official journal of the Movement Disorder Society - 1 Oct 2013
Mirelman Anat, Heman Talia, Yasinovsky Kira, Thaler Avner, Gurevich Tanya, Marder Karen, Bressman Susan, Bar-Shira Anat, Orr-Urtreger Avi, Giladi Nir, Hausdorff Jeffrey M
Abstract excerpt
Patients with Parkinson's disease (PD) who carry the G2019S mutation (a glycine to serine substitution at amino acid 2019) in the leucine-rich repeat kinase 2 (LRRK2) gene are generally believed to be clinically indistinguishable from patients with sporadic PD. There are, however, conflicting reports on the relationship between the mutation and the motor phenotype. We quantitatively compared gait and mobility in...
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