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Article

Sensor-based gait analysis in the premotor stage of LRRK2 G2019S-associated Parkinson's disease.

Parkinsonism & related disorders - 1 May 2022

Sánchez-Rodríguez Antonio, Tirnauca Cristina, Salas-Gómez Diana, Fernández-Gorgojo Mario, Martínez-Rodríguez Isabel, Sierra María, González-Aramburu Isabel, Stan Diana, Gutierrez-González Angela, Meissner Johannes M, Andrés-Pacheco Javier, Rivera-Sánchez María, Sánchez-Peláez María Victoria, Sánchez-Juan Pascual, Infante Jon

Abstract excerpt

INTRODUCTION: There is a need for biomarkers to monitor the earliest phases of Parkinson's disease (PD), especially in premotor stages. Here, we studied whether there are early gait alterations in carriers of the G2019S mutation of LRRK2 that can be detected by means of an inertial sensor system. METHODS: Twenty-one idiopathic PD patients, 20 LRRK2-G2019S PD, 27 asymptomatic carriers of LRRK2-G2019S mutation...

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PMID: 35421781
DOI: 10.1016/j.parkreldis.2022.03.020

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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