Article
Gait alterations in healthy carriers of the LRRK2 G2019S mutation.
Annals of neurology - 1 Jan 2011
Mirelman Anat, Gurevich Tanya, Giladi Nir, Bar-Shira Anat, Orr-Urtreger Avi, Hausdorff Jeffrey M
Abstract excerpt
To test for an association between the LRRK2-G2019S mutation and gait, we studied 52 first-degree relatives of patients with Parkinson's disease (PD) who carry this mutation. An accelerometer quantified gait during usual-walking, fast-walking, and dual-tasking. Noncarriers (n = 27) and carriers (n = 25) were similar with respect to age, gender, height, and gait speed during all conditions. During dual-tasking and...
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