Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Aberrant expression of EZH2 is associated with pathological findings and P53 alteration.

Anticancer research - 1 Oct 2013

Shiogama Sunao, Yoshiba Sayaka, Soga Daisuke, Motohashi Hiromi, Shintani Satoru

Abstract excerpt

AIM: Enhancer of zeste homolog-2 (EZH2) and B lymphoma Mo-MLV insertion region-1 homolog (BMI1) are members of the polycomb group of proteins, which function as transcriptional repressors through chromatin modification. EZH2 forms part of the polycomb repressive complex (PRC)-2, while BMI1 is a component of PRC1. Previous studies have shown that EZH2 is highly expressed in various type of cancers. Expression of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Disease-Free Survival
Share to Enhancer of Zeste Homolog 2 Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Kaplan-Meier Estimate

Share to Lymphatic Metastasis

Share to Mouth Neoplasms

Share to Neoplasm Invasiveness

Share to Polycomb Repressive Complex 1

Share to Polycomb Repressive Complex 2

Source

Identifiers

PMID: 24122997

Genes

BMI1
PRC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Aberrant expression of EZH2 is associated with pathological findings and P53 alteration.PMID 24122997Read ↗

Aberrant expression of EZH2 is associated with a poor outcome and P53 alteration in squamous cell carcinoma of the esophagus.Semantic proximity Read ↗

EZH2 and BMI1 inversely correlate with prognosis and TP53 mutation in breast cancer.Semantic proximity Read ↗

Multifaceted role of the polycomb-group gene EZH2 in hematological malignancies.Semantic proximity Read ↗

Overexpression of EZH2 is associated with clinicopathological parameters and poor prognosis in gliomasSemantic proximity Read ↗

Epigenetic regulation of signaling pathways in cancer: role of the histone methyltransferase EZH2.Semantic proximity Read ↗

EZH2-associated tumor malignancy: A prominent target for cancer treatment.Semantic proximity Read ↗

Aberrations of EZH2 in cancer.Semantic proximity Read ↗

Mutations in EZH2 are associated with poor prognosis for patients with myeloid neoplasmsSemantic proximity Read ↗

Targeting EZH2 in cancer.Semantic proximity Read ↗

The correlation of EZH2 expression with the progression and prognosis of hepatocellular carcinomaSemantic proximity Read ↗

EZH2 promotes malignant phenotypes and is a predictor of oral cancer development in patients with oral leukoplakia.Semantic proximity Read ↗

Polycomb repressive complex's evolutionary conserved function: the role of EZH2 status and cellular background.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.