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Article

Polycomb repressive complex's evolutionary conserved function: the role of EZH2 status and cellular background.

Clinical epigenetics - 1 Jan 2016

Gall Trošelj Koraljka, Novak Kujundzic Renata, Ugarkovic Djurdjica

Abstract excerpt

When assembled in multiprotein polycomb repressive complexes (PRCs), highly evolutionary conserved polycomb group (PcG) proteins epigenetically control gene activity. Although the composition of PRCs may vary considerably, it is well established that the embryonic ectoderm development (EED) 1, suppressor of zeste (SUZ) 12, and methyltransferase enhancer of zeste (EZH2)-containing complex, PRC2, which is abundant...

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Identifiers

PMID: 27239242
DOI: 10.1186/s13148-016-0226-1
PMCID: PMC4882774

Genes

EED

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