Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Upregulation of Membrane‐Bound <scp>CD</scp>40L on <scp>CD</scp>4<sup>+</sup> T cells in Women with Primary Sjögren's Syndrome

12 Oct 2013

Abstract excerpt

Epigenetic deregulation of genes encoded on the X chromosome as reported for CD40L in lupus could explain the female predominance of autoimmune diseases. We compared CD40L expression on CD4(+) T cells from primary Sjögren's syndrome (pSS) women and healthy controls and investigated DNA methylation patterns of the promoter and enhancer regions of CD40L. The expression of CD40L on activated CD4(+) T cells was...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Immunotherapy and Immune Responses
Share to Salivary Gland Disorders and Functions
Share to T-cell and B-cell Immunology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 24117612
DOI: 10.1111/sji.12121

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Upregulation of Membrane‐Bound <scp>CD</scp>40L on <scp>CD</scp>4<sup>+</sup> T cells in Women with Primary Sjögren's SyndromePMID 24117612Read ↗

DNA demethylation of CD40L in CD4+ T cells from women with systemic sclerosis: A possible explanation for female susceptibilitySemantic proximity Read ↗

Overlap between differentially methylated DNA regions in blood B lymphocytes and genetic at-risk loci in primary Sjögren's syndrome.Semantic proximity Read ↗

Genome-wide DNA methylation patterns in monocytes derived from patients with primary Sjogren syndromeSemantic proximity Read ↗

Genome‐Wide DNA Methylation Patterns in Naive CD4+ T Cells From Patients With Primary Sjögren's SyndromeSemantic proximity Read ↗

CD40L demethylation in CD4(+) T cells from women with rheumatoid arthritis.Semantic proximity Read ↗

Immunoglobulin M levels inversely correlate with CD40 ligand promoter methylation in patients with primary biliary cirrhosis.Semantic proximity Read ↗

Hypomethylation and overexpression of ITGAL (CD11a) in CD4+ T cells in systemic sclerosisSemantic proximity Read ↗

Mutations of CD40 ligand in two patients with hyper-IgM syndrome.Semantic proximity Read ↗

B cells in Sjögren's syndrome: indications for disturbed selection and differentiation in ectopic lymphoid tissueSemantic proximity Read ↗

A novel mutation in the CD40 ligand gene in a Chinese boy with X-linked hyper-IgM syndrome.Semantic proximity Read ↗

Clinical and molecular characterization of X-linked hyper-IgM syndrome patients in China.Semantic proximity Read ↗

The polymorphism p.G219R of CD40L does not cause immunological alterations in vivo: conclusions from a X-linked hyper IgM syndrome kindred.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.