Article
Detection of homologous recombination events in bacterial genomes.
PloS one - 1 Jan 2013
Wang Wei-Bung, Jiang Tao, Gardner Shea
Abstract excerpt
We study the detection of mutations, sequencing errors, and homologous recombination events (HREs) in a set of closely related microbial genomes. We base the model on single nucleotide polymorphisms (SNPs) and break the genomes into blocks to handle the rearrangement problem. Then we apply a dynamic programming algorithm to model whether changes within each block are likely a result of mutations, sequencing...
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