Article
Identification and use of biomarkers in treatment strategies for triple-negative breast cancer subtypes.
The Journal of pathology - 1 Jan 2014
Lehmann Brian D, Pietenpol Jennifer A
Abstract excerpt
Triple-negative breast cancer (TNBC) is a heterogeneous disease with distinct molecular subtypes that respond differentially to chemotherapy and targeted agents. The absence of high-frequency molecular alterations and a limited number of known biomarkers have limited the development of therapeutic strategies for the disease. Herein, we summarize the results of the first round of targeted therapy approaches in...
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