Targeting Triple‐Negative Breast Cancer: Resistance Mechanisms and Therapeutic Advancements

Abstract excerpt

BACKGROUND: Triple-negative breast cancer (TNBC) is one of the most heterogeneous and menacing forms of breast cancer, with no sustainable cure available in the current treatment landscape. Its lack of targets makes it highly unresponsive to various treatment modalities, which is why chemotherapy continues to be the primary form of treatment, despite the high rates of patients developing chemoresistance. In...