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Article

IFNα Inducible Models of Murine SLE

1 Jan 2013

Abstract excerpt

The role of type I interferons (IFNs) in SLE pathogenesis has been a subject of intense investigation in the last decade. The strong link between type I IFNs and SLE was initially provided by ex vivo studies showing that exposure of peripheral blood mononuclear cells to immune complexes from SLE patients elicits a signature of IFN inducible genes and was then further highlighted by human genetic studies. The...

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PMID: 24106491
DOI: 10.3389/fimmu.2013.00306

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