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Article

Filaggrin loss-of-function mutations and atopic dermatitis as risk factors for hand eczema in apprentice nurses: part II of a prospective cohort study.

Contact dermatitis - 1 Mar 2014

Visser Maaike J, Verberk Maarten M, Campbell Linda E, McLean W H Irwin, Calkoen Florentine, Bakker Jan G, van Dijk Frank J H, Bos Jan D, Kezic Sanja

Abstract excerpt

BACKGROUND/OBJECTIVES: Environmental exposure and personal susceptibility both contribute to the development of hand eczema. In this study, we investigated the effect of loss-of-function mutations in the filaggrin gene (FLG), atopic dermatitis and wet work exposure on the development of hand eczema in apprentice nurses. METHODS: Dutch apprentice nurses were genotyped for the four most common FLG mutations; atopic...

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Source

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Identifiers

PMID: 24102300
DOI: 10.1111/cod.12139
PMCID: PMC4357292

Genes

FLG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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