Article
Antifungal resistance does not necessarily affect Candida glabrata fitness.
Journal of chemotherapy (Florence, Italy) - 1 Feb 2014
Borghi Elisa, Andreoni Stefano, Cirasola Daniela, Ricucci Valentina, Sciota Rita, Morace Giulia
Abstract excerpt
Although there has been an overall good coverage of Candida glabrata infections by the echinocandins, emergence of antifungal resistance during therapy has been reported. We investigated, by using an invertebrate host model, the fitness of sequential C. glabrata isolates with different echinocandins susceptibility patterns. The studied strains were isolated from a case of recurrent fungemia with a fatal outcome...
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