Article
Impact of CYP2C19 polymorphism on platelet function tests and coagulation and inflammatory biomarkers in patients undergoing percutaneous coronary intervention.
Journal of atherosclerosis and thrombosis - 1 Jan 2014
Kaikita Koichi, Ono Takamichi, Iwashita Satomi, Nakayama Naoki, Sato Koji, Horio Eiji, Nakamura Shinichi, Tsujita Kenichi, Tayama Shinji, Hokimoto Seiji, Sakamoto Tomohiro, Nakao Koichi, Oshima Shuichi, Sugiyama Seigo, Ogawa Hisao
Abstract excerpt
AIM: Carriers of the reduced-function CYP2C19 allele receiving dual antiplatelet therapy (DAPT) with aspirin and clopidogrel exhibit diminished platelet inhibition and an increased risk of events. The purpose of this study was to investigate the effects of CYP2C19 gene variants on platelet function tests and coagulation and inflammatory biomarkers in patients undergoing elective percutaneous coronary intervention...
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