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Carcinogenesis of Pancreatic Adenocarcinoma: Precursor Lesions

30 Sept 2013

Abstract excerpt

Pancreatic adenocarcinoma displays a variety of molecular changes that evolve exponentially with time and lead cancer cells not only to survive, but also to invade the surrounding tissues and metastasise to distant sites. These changes include: genetic alterations in oncogenes and cancer suppressor genes; changes in the cell cycle and pathways leading to apoptosis; and also changes in epithelial to mesenchymal...

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PMID: 24084722
DOI: 10.3390/ijms141019731

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