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Article

Genomic identification of a novel co-trimoxazole resistance genotype and its prevalence amongst Streptococcus pneumoniae in Malawi.

The Journal of antimicrobial chemotherapy - 1 Feb 2014

Cornick Jennifer E, Harris Simon R, Parry Christopher M, Moore Michael J, Jassi Chikondi, Kamng'ona Arox, Kulohoma Benard, Heyderman Robert S, Bentley Stephen D, Everett Dean B

Abstract excerpt

OBJECTIVES: This study aimed to define the molecular basis of co-trimoxazole resistance in Malawian pneumococci under the dual selective pressure of widespread co-trimoxazole and sulfadoxine/pyrimethamine use. METHODS: We measured the trimethoprim and sulfamethoxazole MICs and analysed folA and folP nucleotide and translated amino acid sequences for 143 pneumococci isolated from carriage and invasive disease in...

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Identifiers

PMID: 24080503
DOI: 10.1093/jac/dkt384
PMCID: PMC3886935

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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