Article
Molecular insights of co-trimoxazole resistance genes in Haemophilus influenzae isolated in Malaysia.
Tropical biomedicine - 1 Dec 2013
Mohd-Zain Z, Kamsani N H, Ahmad N
Abstract excerpt
In the last few decades, co-trimoxazole (SXT), an antibacterial combination of trimethoprim and sulfamethoxazole, has been used for treatment of upper respiratory tract infection due to Haemophilus influenzae. The usage of this antibiotic has become less important due to emergence of SXT-resistant strains worldwide. Most reports associate SXT resistance to the presence of variants of dihydrofolate reductase...
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