Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

EIF4G1 R1205H and VPS35 D620N mutations are rare in Parkinson's disease from South Africa.

Neurobiology of aging - 1 Feb 2014

Blanckenberg Janine, Ntsapi Claudia, Carr Jonathan A, Bardien Soraya

Abstract excerpt

The R1205H mutation in the eukaryotic translation initiation factor 4G1 (EIF4G1) gene and the D620N mutation in the vacuolar protein sorting 35 (VPS35) gene were recently found in patients with autosomal dominant or sporadic forms of Parkinson's disease (PD). In the present study, 418 South African PD patients and 528 control subjects of diverse ethnicities were screened using the KASP (Kompetitive Allele...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Disease Susceptibility
Share to Eukaryotic Initiation Factor-4G

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genotyping Techniques

Share to Mutation

Share to Mutation Rate

Share to Parkinsonian Disorders

Share to South Africa

Share to Vesicular Transport Proteins

Source

Identifiers

PMID: 24080171
DOI: 10.1016/j.neurobiolaging.2013.08.023

Genes

VPS35

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

EIF4G1 R1205H and VPS35 D620N mutations are rare in Parkinson's disease from South Africa.PMID 24080171Read ↗

D620N mutation in the VPS35 gene and R1205H mutation in the EIF4G1 gene are uncommon in the Greek population.Semantic proximity Read ↗

Leucine rich repeat kinase 2 (LRRK2) GLY2019SER mutation is absent in a second cohort of Nigerian Africans with Parkinson diseaseSemantic proximity Read ↗

Leucine rich repeat kinase 2 (LRRK2) gly2019ser mutation is absent in a second cohort of nigerian africans with parkinson diseaseSemantic proximity Read ↗

VPS35 and EIF4G1 mutations are rare in Parkinson's disease among Indians.Semantic proximity Read ↗

Assessing the prevalence of PINK1 genetic variants in South African patients diagnosed with early- and late-onset Parkinson's disease.Semantic proximity Read ↗

Frequency of the ASP620ASN mutation in VPS35 and Arg1205His mutation in EIF4G1 in familial Parkinson's disease from South Italy.Semantic proximity Read ↗

VPS35 Asp620Asn and EIF4G1 Arg1205His mutations are rare in Parkinson disease from southwest China.Semantic proximity Read ↗

Screening of the glucocerebrosidase (GBA) gene in South Africans of African ancestry with Parkinson's disease.Semantic proximity Read ↗

Variants in eukaryotic translation initiation factor 4G1 in sporadic Parkinson's disease.Semantic proximity Read ↗

Using KASP technique to screen LRRK2 G2019S mutation in a large Tunisian cohort.Semantic proximity Read ↗

Frequency of the D620N mutation in VPS35 in Parkinson disease.Semantic proximity Read ↗

Glucocerebrosidase mutations are not a common risk factor for Parkinson disease in North Africa.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.