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Article

Histotype-genotype correlation in 36 high-grade endometrial carcinomas.

The American journal of surgical pathology - 1 Sept 2013

Hoang Lien N, McConechy Melissa K, Köbel Martin, Han Guangming, Rouzbahman Marjan, Davidson Ben, Irving Julie, Ali Rola H, Leung Sam, McAlpine Jessica N, Oliva Esther, Nucci Marisa R, Soslow Robert A, Huntsman David G, Gilks C Blake, Lee Cheng-Han

Abstract excerpt

Endometrioid, serous, and clear cell carcinomas are the major types of endometrial carcinoma. Histologic distinction between these different tumor types can be difficult in high-grade cases, in which significant interobserver diagnostic disagreement exists. Endometrioid and clear cell carcinomas frequently harbor ARID1A and/or PTEN mutations. Serous carcinoma acquires TP53 mutations/inactivation at onset, with a...

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Share to Adenocarcinoma, Clear Cell
Share to Carcinoma, Endometrioid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cyclin-Dependent Kinase Inhibitor p16

Share to Endometrial Neoplasms

Share to Neoplasms, Cystic, Mucinous, and Serous

Share to Observer Variation

Share to Protein Phosphatase 2

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Source

Identifiers

PMID: 24076778
DOI: 10.1097/PAS.0b013e31828c63ed

Genes

PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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