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Article

Interobserver Agreement in Endometrial Carcinoma Histotype Diagnosis Varies Depending on The Cancer Genome Atlas (TCGA)-based Molecular Subgroup.

The American journal of surgical pathology - 1 Feb 2017

Hoang Lien N, Kinloch Mary A, Leo Joyce M, Grondin Katherine, Lee Cheng-Han, Ewanowich Carol, Köbel Martin, Cheng Angela, Talhouk Aline, McConechy Melissa, Huntsman David G, McAlpine Jessica N, Soslow Robert A, Gilks C Blake

Abstract excerpt

The Cancer Genome Atlas recently identified a genomic-based molecular classification of endometrial carcinomas, with 4 molecular categories: (1) ultramutated (polymerase epsilon [POLE] mutated), (2) hypermutated (microsatellite instability), (3) copy number abnormalities-low, and (4) copy number abnormalities-high. Two studies have since proposed models to classify endometrial carcinomas into 4 molecular...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28079598
DOI: 10.1097/PAS.0000000000000764

Genes

POLE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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