Article
Genetic analysis of the S100B gene in Chinese patients with Parkinson disease.
Neuroscience letters - 25 Oct 2013
Guo Yi, Yang Huarong, Deng Xiong, Song Zhi, Yang Zhijian, Xiong Wei, Yuan Lamei, Xu Hongbo, Deng Sheng, Deng Hao
Abstract excerpt
There is growing evidence that genetic abnormalities play an important role in the pathogenesis of Parkinson disease (PD). At least 18 genetic loci and 13 disease-related genes for parkinsonism have been identified. The S100 calcium-binding beta (S100B), which is expressed and secreted by astrocytes, has been found to be associated with PD. To evaluate whether the S100B variants are related to PD in Chinese Han...
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