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Article

Bone-stromal cells up-regulate tumourigenic markers in a tumour-stromal 3D model of prostate cancer.

Molecular cancer - 30 Sept 2013

Windus Louisa C E, Glover Tristan T, Avery Vicky M

Abstract excerpt

BACKGROUND: The cellular and molecular mechanisms that mediate interactions between tumour cells and the surrounding bone stroma are to date largely undetermined in prostate cancer (PCa) progression. The purpose of this study was to evaluate the role of alpha 6 and beta 1 integrin subunits in mediating tumour-stromal interactions. METHODS: Utilising 3D in vitro assays we evaluated and compared 1. Monocultures of...

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Identifiers

PMID: 24073816
DOI: 10.1186/1476-4598-12-112
PMCID: PMC3850923

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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