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Targeting PKCε by miR‐143 regulates cell apoptosis in lung cancer

23 Sept 2013

Abstract excerpt

Non-small cell lung cancer (NSCLC) is one of the most common causes for lung cancer and cancer-related death. The imbalance between cell proliferation and apoptosis was suggested to play an important role in cancer pathogenesis and PKCε is one of the widely recognized targets. Here, we demonstrate that miR-143 is aberrantly downregulated in NSCLC tissue and negatively correlates with expression of PKCε. We show...

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PMID: 24070896
DOI: 10.1016/j.febslet.2013.09.018

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