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Strategy for Sensitive and Specific Detection of Yersinia pestis in Skeletons of the Black Death Pandemic

17 Sept 2013

Abstract excerpt

Yersinia pestis has been identified as the causative agent of the Black Death pandemic in the 14(th) century. However, retrospective diagnostics in human skeletons after more than 600 years are critical. We describe a strategy following a modern diagnostic algorithm and working under strict ancient DNA regime for the identification of medieval human plague victims. An initial screening and DNA quantification...

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PMID: 24069445
DOI: 10.1371/journal.pone.0075742

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