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Early Divergent Strains of Yersinia pestis in Eurasia 5,000 Years Ago

1 Oct 2015

Abstract excerpt

The bacteria Yersinia pestis is the etiological agent of plague and has caused human pandemics with millions of deaths in historic times. How and when it originated remains contentious. Here, we report the oldest direct evidence of Yersinia pestis identified by ancient DNA in human teeth from Asia and Europe dating from 2,800 to 5,000 years ago. By sequencing the genomes, we find that these ancient plague strains...

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PMID: 26496604
DOI: 10.1016/j.cell.2015.10.009

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