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Article

Generation of Unique Poliovirus RNA Replication Organelles

26 Feb 2014

Abstract excerpt

Poliovirus (PV), a model for interactions of picornaviruses with host cells, replicates its genomic RNA in association with cellular membranes. The origin of PV replication membranes has not been determined. Hypotheses about the origin of replication membranes, based largely on localization of viral proteins, include modification of coat protein complex I (COPI) and/or COPII secretory pathway vesicles and...

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PMID: 24570367
DOI: 10.1128/mbio.00833-13

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