Article
Protein N-myristoylation in Escherichia coli: reconstitution of a eukaryotic protein modification in bacteria.
Proceedings of the National Academy of Sciences of the United States of America - 1 Feb 1990
Duronio R J, Jackson-Machelski E, Heuckeroth R O, Olins P O, Devine C S, Yonemoto W, Slice L W, Taylor S S, Gordon J I
Abstract excerpt
Protein N-myristoylation refers to the covalent attachment of a myristoyl group (C14:0), via amide linkage, to the NH2-terminal glycine residue of certain cellular and viral proteins. Myristoyl-CoA:protein N-myristoyltransferase (NMT) catalyzes this cotranslational modification. We have developed...
Topics
- Acyltransferases
- Amino Acid Sequence
- Base Sequence
- Escherichia coli
- Genes, Fungal
- Kinetics
- Macromolecular Substances
- Molecular Sequence Data
- Mutation
- Myristic Acid
- Myristic Acids
- Oligonucleotide Probes
- Plasmids
- Protein Processing, Post-Translational