Article
Glucose-6-phosphate Dehydrogenase: a Biomarker and Potential Therapeutic Target for Cancer
31 Jan 2014
Abstract excerpt
Re-programming of metabolic pathways is a hallmark of pathological changes in cancer cells. The expression of certain genes that directly control the rate of key metabolic pathways including glycolysis, lipogenesis and nucleotide synthesis is dysregulated for the adaptation and progression of tumor cells to become more aggressive phenotypes. The pentose phosphate pathway controlled by glucose- 6-phosphate...
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