Article
RNA polymerase II mutants defective in transcription of a subset of genes.
Molecular and cellular biology - 1 Mar 1990
Scafe C, Nonet M, Young R A
Abstract excerpt
Saccharomyces cerevisiae RNA polymerase II conditional mutants that selectively disrupt the synthesis of specific mRNAs were isolated. At the permissive temperature, several of the mutants were inositol auxotrophs as a result of inadequate induction of INO1 transcription. The transcriptional defects exhibited by one of these Ino- mutants (rpb2-2) were further investigated. The induction of GAL10 and HIS4...
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