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Article

Kindlin‐2 is expressed in malignant mesothelioma and is required for tumor cell adhesion and migration

2 Feb 2010

Abstract excerpt

Kindlin-2 is a novel integrin-interacting focal adhesion protein that belongs to the Kindlin family. Focal adhesion proteins control cytoskeleton dynamics and promote cancer cell growth, survival, migration and metastasis. Little is known, however, about expression of Kindlin-2 in association with human cancer. We now reveal high Kindlin-2 expression in malignant mesothelioma (MM) cell lines using an...

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Identifiers

PMID: 20127858
DOI: 10.1002/ijc.25223

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Kindlin‐2 is expressed in malignant mesothelioma and is required for tumor cell adhesion and migrationPMID 20127858Read ↗

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Re-expression of the tumor suppressor NF2/merlin inhibits invasiveness in mesothelioma cells and negatively regulates FAKSemantic proximity Read ↗

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