Article
Effect of a GFOD2 variant on responses in total and LDL cholesterol in Mexican subjects with hypercholesterolemia after soy protein and soluble fiber supplementation.
Gene - 15 Dec 2013
Guevara-Cruz Martha, Lai Chao-Qiang, Richardson Kris, Parnell Laurence D, Lee Yu-Chi, Tovar Armando R, Ordovás Jose M, Torres Nimbe
Abstract excerpt
BACKGROUND: Although dietary treatments can successfully reduce blood lipids in hypercholesterolemic subjects, individual variation in that response has on occasion been linked to allelic differences. SNP rs12449157 has shown association with HDL-C concentrations in GWAS and falls in the glucose-fructose oxidoreductase domain containing 2 (GFOD2) locus. Of interest, previous data suggest that this SNP may be...
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