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Complement-dependent virion lysis mediated by dengue-Zika virus cross-reactive antibodies correlates with protection from severe dengue disease

2024-06-04

Abstract excerpt

Primary infection with one of four dengue virus serotypes (DENV1-4) may generate antibodies that protect or enhance subsequent secondary heterotypic infections. However, the characteristics of heterotypic cross-reactive antibodies associated with protection from symptomatic infection and severe disease are not well-defined. We selected plasma samples collected before a secondary DENV heterotypic infection that was...

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Literature Corpus work
0d107df5-f5a5-5d5c-811a-fe1b5a84ff5d
DOI
10.1101/2024.06.03.24308395
Open publication

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Complement-dependent virion lysis mediated by dengue-Zika virus cross-reactive antibodies correlates with protection from severe dengue diseaseDOI 10.1101/2024.06.03.24308395
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