Article
Enhanced Cordycepin Production in Caterpillar Medicinal Mushroom, Cordyceps militaris (Ascomycetes), Mutated by a Multifunctional Plasma Mutagenesis System.
International journal of medicinal mushrooms - 1 Jan 2020
Zhang Hucheng, Deng Lina, Zhang Zhengtian, Guan Yusen, Li Bo, Yang Jun, Fan Haitao, Yang Guowei, Chen Xiaofeng, Zhang Jinjun, Xin Xiulan, Vriesekoop Frank
Abstract excerpt
A multifunctional plasma mutation system (MPMS) method was used to create high cordycepin-yielding mutations from wild Cordyceps militaris, which yielded many viable mutants, many of which produced more cordycepin compared to the wild strain. One particular mutant strain (GYS60) produced 7.883 mg/mL, which is much higher than those reported to date and is more than 20 times higher than that of the wild strain,...
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