Article
Forward chemical genetic screening.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2014
Choi Hyunmo, Kim Jun-Young, Chang Young Tae, Nam Hong Gil
Abstract excerpt
Chemical genetics utilizes small molecules to perturb biological processes. Unlike conventional genetics methods, which involve the alteration of genetic information mostly with lasting effects, chemical genetics allows temporary and reversible alterations of biological processes. Furthermore, it enables the alteration of biological processes in a dose-dependent manner, providing an advantage over conventional...
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