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Article

Using a reverse genetics approach to investigate small-molecule activity.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2014

Doyle Siamsa M, Robert Stéphanie

Abstract excerpt

Chemical genomics is a highly effective approach for understanding complex and dynamic biological processes in plants. A chemical activity can be investigated by a reverse genetics strategy, for which a huge abundance and diversity of Arabidopsis thaliana mutants are readily available for exploitation. Here we present an approach to characterize a chemical of interest, as well as examples of studies demonstrating...

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PMID: 24306862
DOI: 10.1007/978-1-62703-592-7_6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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