Article
Interaction of genetic and environmental factors in the pathogenesis of insulin-dependent diabetes mellitus.
Clinica chimica acta; international journal of clinical chemistry - 17 Jan 1997
Akerblom H K, Knip M, Hyöty H, Reijonen H, Virtanen S, Savilahti E, Ilonen J
Abstract excerpt
The current concept of the pathogenesis of insulin-dependent diabetes mellitus (IDDM) is based on the view that environmental factors, either alone or in combination, trigger in a genetically, susceptible individual an autoimmune process which leads to the destruction of the insulin-secreting beta cells. The identification of environmental risk factors for IDDM is of utmost importance with regard to possibilities...
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