Article
No evidence of somatic aryl hydrocarbon receptor interacting protein mutations in sporadic endocrine neoplasia.
Endocrine-related cancer - 1 Sept 2007
Raitila A, Georgitsi M, Karhu A, Tuppurainen K, Mäkinen M J, Birkenkamp-Demtröder K, Salmenkivi K, Orntoft T F, Arola J, Launonen V, Vahteristo P, Aaltonen L A
Abstract excerpt
Germline mutations in the aryl hydrocarbon receptor interacting protein (AIP) gene were recently observed in patients with pituitary adenoma predisposition (PAP). Though AIP mutation-positive individuals with prolactin-, mixed growth hormone/prolactin-, and ACTH-producing pituitary adenomas as well as non-secreting pituitary adenomas have been reported, most mutation-positive patients have had growth...
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