Article
Evolution of the tryptophan synthetase of fungi. Analysis of experimentally fused Escherichia coli tryptophan synthetase alpha and beta chains.
The Journal of biological chemistry - 5 Feb 1990
Burns D M, Horn V, Paluh J, Yanofsky C
Abstract excerpt
During evolution of fungi, the separate tryptophan synthetase alpha and beta polypeptides of bacteria appear to have been fused in the order alpha-beta rather than the beta-alpha order that would be predicted from the order of the corresponding structural genes in all bacteria. We have fused the...
Topics
- Amino Acid Sequence
- Biological Evolution
- Cloning, Molecular
- Escherichia coli
- Fungi
- Genes, Bacterial
- Genes, Fungal
- Macromolecular Substances
- Molecular Sequence Data
- Mutation
- Oligonucleotide Probes
- Plasmids
- Recombinant Fusion Proteins
- Restriction Mapping
- Sequence Homology, Nucleic Acid
- Tryptophan Synthase