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Article

Steps to ensure accuracy in genotype and SNP calling from Illumina sequencing data.

BMC genomics - 1 Jan 2012

Liu Qi, Guo Yan, Li Jiang, Long Jirong, Zhang Bing, Shyr Yu

Abstract excerpt

BACKGROUND: Accurate calling of SNPs and genotypes from next-generation sequencing data is an essential prerequisite for most human genetics studies. A number of computational steps are required or recommended when translating the raw sequencing data into the final calls. However, whether each step does contribute to the performance of variant calling and how it affects the accuracy still remain unclear, making...

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PMID: 23281772
DOI: 10.1186/1471-2164-13-S8-S8
PMCID: PMC3535703

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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