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Article

Inhibition of hyaluronan synthase 2 reduces the abnormal migration rate of keloid keratinocytes.

Journal of burn care & research : official publication of the American Burn Association - 1 Jan 2000

Supp Dorothy M, Hahn Jennifer M, McFarland Kevin L, Glaser Kathryn

Abstract excerpt

Keloids are fibroproliferative scars that spread beyond the original wound boundary and are very resistant to treatment. Development of highly effective therapies requires a comprehensive understanding of the mechanisms regulating keloid formation. Previous studies indicated that keloid keratinoc...

Read the complete abstract on PubMed

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24043232
DOI: 10.1097/BCR.0b013e3182a2a9dd

Genes

HAS2
HAS1
HAS3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24043232-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

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Inhibition of hyaluronan synthase 2 reduces the abnormal migration rate of keloid keratinocytes.PMID 24043232Read ↗

Human skin long noncoding RNA WAKMAR1 regulates wound healing by enhancing keratinocyte migrationSemantic proximity Read ↗

Abnormal accumulation of hyaluronan matrix diminishes contact inhibition of cell growth and promotes cell migration.Semantic proximity Read ↗

Keratin-Mediated Selective Inhibition in Proliferation and Selective Apoptosis of Keloid FibroblastsSemantic proximity Read ↗

Treatment of keloids through Runx2 siRNA‑induced inhibition of the PI3K/AKT signaling pathwaySemantic proximity Read ↗

Gene Expression Profile of Isolated Dermal Vascular Endothelial Cells in KeloidsSemantic proximity Read ↗

Astragaloside IV alleviates skin fibrosis by modulating fibroblast phenotype in keloids.Semantic proximity Read ↗

Keloid microRNA expression analysis and the influence of miR-199a-5p on the proliferation of keloid fibroblastsSemantic proximity Read ↗

Deep and superficial keloid fibroblasts contribute differentially to tissue phenotype in a novel in vivo model of keloid scar.Semantic proximity Read ↗

A Role for Neuregulin-1 in Promoting Keloid Fibroblast Migration via ErbB2-mediated SignalingSemantic proximity Read ↗

Involvement of hyaluronan in regulation of fibroblast phenotype.Semantic proximity Read ↗

Hypoxia Upregulates VEGF Production in Keloid FibroblastsSemantic proximity Read ↗

Dose- and time-dependent effects of hyaluronidase on structural cells and the extracellular matrix of the skinSemantic proximity Read ↗

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