Article
SIL-TAL1 rearrangement is related with poor outcome: a study from a Chinese institution.
PloS one - 1 Jan 2013
Wang Di, Zhu Guangrong, Wang Na, Zhou Xiaoxi, Yang Yunfan, Zhou Shiqiu, Xiong Jie, He Jing, Jiang Lijun, Li Chunrui, Xu Danmei, Huang Liang, Zhou Jianfeng
Abstract excerpt
SIL-TAL1 rearrangement is common in T-cell acute lymphoblastic leukemia (T-ALL), however its prognostic implication remains controversial. To investigate the clinical characteristics and outcome of this subtype in Chinese population, we systemically reviewed 62 patients with newly diagnosed T-ALL, including 15 patients with SIL-TAL1 rearrangement. We found that SIL-TAL1(+) T-ALL was characterized by higher white...
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