Article
Sulfolipid accumulation in Mycobacterium tuberculosis disrupted in the mce2 operon.
Journal of microbiology (Seoul, Korea) - 1 Jun 2011
Marjanovic Olivera, Iavarone Anthony T, Riley Lee W
Abstract excerpt
Mycobacterium tuberculosis, the causative agent of tuberculosis, has a lipid-rich cell wall that serves as an effective barrier against drugs and toxic host cell products, which may contribute to the organism's persistence in a host. M. tuberculosis contains four homologous operons called nice (mce1-4) that encode putative ABC transporters involved in lipid importation across the cell wall. Here, we analyzed the...
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