Article
No association between attention-deficit hyperactivity disorder and catechol-O-methyltransferase gene in Chinese.
Yi chuan xue bao = Acta genetica Sinica - 1 Aug 2005
Jiang San-Duo, Wu Xiao-Dong, Zhang Ye, Tang Guo-Mei, Qian Yi-Ping, Wang Dong-Xiang
Abstract excerpt
Previous studies suggested that the catecholaminergic systems may be involved in the pathogenesis of attention-deficit hyperactivity disorder(ADHD). Since catechel-O-methyltransferase (COMT) is an enzyme involved in the degradation of catecholaminergic neurotransmitters of the dopaminergic and noradrenergic systems,it is possible that COMT may play a role in ADHD. To test this hypothesis, we used two family-based...
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